A study found that the Respiratory syncytial virus prefusion F (RSVpreF) vaccine significantly reduced severe RSV-related lower respiratory tract disease in older adults, with an efficacy of 91% when compared to a strictly defined control group. The vaccine also showed an efficacy of 90% when compared to a broad control group. Researchers analyzed data from a large US healthcare network, including 7047 older adults, with 223 receiving the RSVpreF vaccine and testing positive for RSV. The vaccine was found to prevent one RSV-related ED or hospitalization encounter for every 250 persons vaccinated in the first season. The study was funded by Pfizer, and some authors disclosed financial ties to the company.
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