New brain mapping research funded by the NIH shows that not all brain cells age the same way, with some being more sensitive to aging than others. The study, published in Nature, found that cells controlling hormones undergo more age-related changes in genetic activity. These results may help in understanding aging brain disorders like Alzheimer’s disease. The study analyzed genetic activity in young and aged mice brains, showing decreases in neuronal gene activity and increases in inflammatory genes with age. Cells surrounding the third ventricle in the hypothalamus were found to be the most sensitive to aging, potentially impacting body metabolism. Further research is needed to explore these findings and their implications for human health.
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Brain mapping reveals cell-specific aging patterns
