Unusual Causes of Kidney Disease: Searching for ‘Zebras’

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Physicians are often advised to consider common conditions over rare ones when diagnosing patients, but this approach may not hold true for kidney diseases and injuries. A recent case highlighted the importance of considering kidney damage as a potential complication of seemingly unrelated conditions. Infections, autoimmune diseases, genetic conditions, medications, cancer treatments, and other factors can all contribute to kidney dysfunction. Non-nephrologists should remain vigilant for kidney involvement in patients with certain symptoms or conditions, while timely referral to a nephrologist can improve outcomes. Collaborative care between primary care clinicians and nephrologists is essential in identifying and managing kidney diseases effectively.

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