A recent study published in Nature Neuroscience explores the connection between tau filaments and extracellular vesicles (EVs) in Alzheimer’s disease (AD). Researchers found that tau filaments are enclosed within EVs enriched in endo-lysosomal proteins in the brains of individuals with AD. These findings offer new insight into the association between tau proteins and EVs, potentially leading to the development of therapeutic strategies for AD and other neurodegenerative disorders. The researchers suggest that targeting EV-associated tau could be a promising approach for developing future therapies and biomarkers for AD. The study highlights the importance of understanding the molecular mechanisms of EV-mediated secretion of tau filaments.
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Study explores association between Tau filaments and extracellular vesicles in Alzheimer’s disease
