Pain and over-the-counter medication

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Pain involves nociceptive, neuropathic, and nociplastic mechanisms. Nociceptive pain comes from injury or inflammation, neuropathic pain results from nerve damage, and nociplastic pain involves altered central nervous system processing. Chronic pain can be managed with over-the-counter (OTC) pain relievers like NSAIDs and paracetamol, but must be used carefully to avoid side effects. OTC pain relievers work by inhibiting specific enzymes or pathways in the body. Combination products like Easolief DUO can provide enhanced relief. Safety considerations should be taken into account, especially for certain populations. Non-pharmacological pain management techniques are also recognized as valuable. Ongoing research is focused on developing more targeted and effective pain relief options.

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