Sepsis is a deadly complication of infection that can lead to acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), both associated with high mortality rates. NETs play a key role in the progression of sepsis by triggering inflammation. A study from Nanjing Medical University shows that medical ozone therapy targeting the AMPK/SR-A1 axis can effectively clear NETs, improving survival rates and lung function in mice with sepsis-induced ALI. This research reveals that ozone treatment reduces NET formation, enhances macrophage function, and mitigates inflammation, offering a promising new approach to managing sepsis-induced ALI. If successful in human trials, ozone therapy could transform treatment for this condition.
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Ozone therapy shows promise in treating sepsis-induced lung injury
