The EARLY TAVR study showed that transcatheter aortic valve replacement (TAVR) is superior to surveillance in patients with severe but asymptomatic aortic stenosis. The study, conducted in the US and Canada, involved 901 patients with no symptoms of aortic stenosis. Results indicated a 50% lower risk of death, stroke, and hospitalization in the TAVR group compared to the surveillance group. Although there was no significant difference in mortality, TAVR significantly reduced hospitalizations. Additionally, the study highlighted the progressive nature of aortic stenosis, with the majority of surveillance patients developing symptoms and undergoing TAVR within a few years.
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