In patients with severe alcohol-associated hepatitis, tapering corticosteroids appears to be as safe and effective as a fixed dose. Corticosteroids are the main treatment for this condition, but infections are a concern in many cases. A study involving 254 patients found that tapering doses of corticosteroids reduced infections, hospitalizations, and drug-related adverse events compared to a fixed dose. Survival rates were similar in both groups. While steroids are still the preferred treatment, researchers are also exploring alternative therapies such as gut microbiome transplantation. This could potentially offer a safer and more effective treatment for severe alcohol-associated hepatitis in the future.
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Tapering Corticosteroids in SAH Appears Safe
