Irish researchers have developed a non-invasive method to study gene activity in the living human brain. By analyzing RNA and DNA collected from electrodes implanted in epilepsy patients’ brains, researchers were able to link gene activity with electrical recordings and gain insight into seizure networks. This breakthrough, published in JCI Insight, has the potential to improve epilepsy surgeries and is the first step towards understanding and treating neurological conditions like Alzheimer’s and Parkinson’s. The study, led by Prof David Henshall, was funded by the HEA North-South Research Programme and FutureNeuro, and involved collaborators from around the world.
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‘Snapshots’ of gene activity in human brain may lead to better treatments for neurological conditions
