A Michigan State University researcher has developed a new model for studying breast cancer that focuses on the E2F5 gene’s role in cancer metastasis. Through the study of genetic models and bioinformatics, the researcher’s lab identified altered regulation of Cyclin D1, a protein linked to metastatic breast tumors. The removal of E2F5 in the mammary gland led to tumor formation, providing insights into tumor progression. This research could help scientists understand how genes impact breast cancer development and metastasis, leading to the potential development of targeted therapies with fewer side effects for different breast cancer subtypes.
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Researchers develop promising new genetic breast cancer model
