Predicting Failure to Rescue Using the Modified Frailty Index

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Age and ASA status may predict survival after an anastomotic leak following colectomy for colorectal cancer, according to new research. The addition of frailty variables, including the ACS-NSQIP mFI-5, did not significantly improve predictive performance. Older age with ASA III classification were strongly associated with failure to rescue (FTR) in patients who experienced anastomotic leaks. The study analyzed data from over 50,000 patients and found no statistical differences in predictive performance between models. Further research is planned to develop risk calculators to better predict FTR in patients with anastomotic leaks. Limitations include retrospective nature and inability to confirm if all fatalities were due to leaks.

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