The National Comprehensive Cancer Network has expanded two cancer genetic risk assessment guidelines to include additional cancer types, such as prostate, endometrial, and gastric cancer. The guidelines provide information on when genetic testing is recommended, specific genetic mutations associated with elevated cancer risk, and appropriate next steps for individuals with these mutations. The updated guidelines also emphasize the importance of genetic counseling and improved screening and prevention strategies. Oncologists are encouraged to ask patients about their family history of cancer and known germline variants at the time of diagnosis to determine if genetic testing is necessary. These guidelines aim to enhance shared decision-making between healthcare providers and patients, improve screening practices, and guide treatment options for individuals with cancer and their families.
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