Interactive atlas unveils immune changes in multiple myeloma

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Multiple Myeloma is an incurable blood cancer with high relapse rates, prompting the need for novel immunotherapies. Researchers have developed an interactive tool based on a single-cell RNA-sequencing atlas of the MM immune microenvironment to guide the development of new treatments. The tool focuses on understanding the tumor-immune microenvironment to overcome resistance mechanisms in MM therapy. The study revealed changes in immune populations during disease progression, highlighting the potential of immune-boosting therapies. The tool is freely accessible and can aid in patient stratification and the development of durable immunotherapeutic strategies in Multiple Myeloma.

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