In aggressive form of breast cancer, response to therapy may contribute to tumor regrowth, study finds

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A recent study from Vanderbilt University suggests that treatment with radiation therapy for triple negative breast cancer (TNBC) may lead to an environment supportive of tumor regrowth. The research found that radiation therapy, while important for survival rates in TNBC patients, can result in increased cancer cell proliferation in an immunosuppressed microenvironment. The study, published in Biomaterials, explores how radiation affects the extracellular matrix in the breast tissue, providing a platform for cancer cells to thrive. Further research aims to develop realistic clinical approaches to enhance the effectiveness of radiation therapy and reduce breast cancer recurrence.

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