The Golgi apparatus plays a crucial role in modifying proteins for cellular function, particularly in T-cells that fight cancer. Research has shown that treating the Golgi with hydrogen sulfide helps T-cells withstand stress in the tumor microenvironment. Cells with more Golgi are better at killing cancer cells and controlling tumors, indicating the potential for using Golgi as a biomarker for selecting strong T-cells for immunotherapy. Sorting T-cells based on Golgi levels could improve cancer treatment outcomes. Further studies are needed to explore Golgi stress in the context of other organelles under tumor-induced stress. Future clinical trials may validate these findings.
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Golgi apparatus plays crucial role in enhancing T-cell function against cancer
