Vaccination against human papilloma virus (HPV) has proven effective in preventing diseases caused by high-risk HPV types. Gardasil 4, approved in 2006, played a key role in lowering cervical cancer rates. Despite past success, cervical cancer remains a significant health concern. The introduction of Gardasil 9 in 2014 broadened immunization efforts. Increasing uptake of vaccinations in young people is a current public health focus. The World Health Organization has endorsed an HPV vaccination campaign with the goal of eradicating cervical cancer. Despite progress, there are still global barriers to immunization. The history of HPV vaccines dates back to the 1950s, with significant milestones in research and development.
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