Fifteen years ago, an HIV vaccine trial in Thailand sponsored by the U.S. Army showed promising results, reducing new infections by more than 31%. However, recent trials of similar vaccines in Africa have not been successful. Long-acting injectables like lenacapavir have changed the landscape of HIV prevention, raising concerns about the future of HIV vaccine research. Experts discuss the importance of continuing vaccine research for choice, durability, and cost reasons. Despite challenges, vaccine research has informed other areas of science and could potentially lead to advancements in finding a cure for HIV.
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Does the world still need an HIV vaccine? Experts say yes
