Clindamycin, a drug with antibacterial and anti-inflammatory properties, remains relevant and safe for treating acne vulgaris. While oral clindamycin is not FDA-approved for acne, both oral and topical formulations are available. Combining clindamycin with other ingredients, like benzoyl peroxide, is recommended to reduce antibiotic resistance and optimize efficacy. A recent triple-combination gel containing clindamycin was approved by the FDA for acne treatment. Although concerns about antibiotic resistance exist, studies show that combination therapy with clindamycin is effective. Dermatologists can address patient concerns through education and emphasizing the low safety risks associated with clindamycin.
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