A new study from the Institute of Neurosciences at the University of Barcelona reveals a molecular mechanism affecting RNA processing in Alzheimer’s patients. The RTP801 protein was found to disrupt the activity of the tRNA ligase complex, impacting protein synthesis and neuronal survival. This discovery may lead to new therapies for neurodegenerative diseases by targeting RTP801 or preserving tRNA ligase activity. The researchers believe that inhibiting RTP801 or preserving tRNA ligase function could mitigate cognitive deficits in Alzheimer’s disease. This innovative approach offers promising therapeutic options for treating neurological disorders in the future.
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New study reveals molecular mechanism in Alzheimer’s disease
