Research has found that therapies delivering hydrogen sulfide to cells may lead to new treatments for obesity and related diseases. Hydrogen sulfide plays a crucial role in liver function, impacting how the liver processes fat and the function of mitochondria. A study using the compound AP39 in mice on a high-fat diet showed a 32% decrease in weight gain over 12 weeks and reduced fat accumulation in the liver. The research suggests that targeting mitochondria with hydrogen sulfide could be a promising approach for treating obesity. This study highlights the potential for developing innovative therapies using hydrogen sulfide to address metabolic diseases.
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