Researchers have developed a new drug, RI-AG03, that shows promise in the treatment of Alzheimer’s by blocking tau build-up in the brain. This drug acts on two regions of the tau protein, preventing it from sticking together and causing aggregation. The drug has been found to be effective in both lab studies and with fruit flies, reducing neurodegeneration and extending lifespan. Unlike current treatments that target only one hotspot, RI-AG03 simultaneously blocks both hotspots, potentially leading to more effective treatments with fewer side effects. Researchers believe this drug could be a breakthrough in treating neurodegenerative diseases like Alzheimer’s.
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