A woman in her 40s was found to have multi-coloured crystals in the vitreous cavity of her left eye during a routine diabetic screening examination. She had a history of proliferative diabetic retinopathy with recurrent vitreous bleeds but was asymptomatic. The crystals were identified as synchysis scintillans, a rare condition where small, freely moving cholesterol crystals accumulate in the vitreous cavity. It is caused by the breakdown of erythrocytes after vitreous hemorrhage. The condition can lead to secondary glaucoma and must be differentiated from other ocular conditions such as asteroid hyalosis, vitreous amyloidosis, and vitritis.
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