Pregnant women with systemic lupus erythematosus are at a higher risk of adverse outcomes such as miscarriage and preterm delivery if they have either high or low levels of serum vitamin D. A study recommended monitoring maternal vitamin D levels during pregnancy and aiming for a range of 40 ng/mL to 59 ng/mL to reduce these risks. The study found a “U-shaped” relationship between maternal vitamin D levels and adverse outcomes, with the highest risks at concentrations below 20 ng/mL and above 60 ng/mL. Monitoring and supplementing with vitamin D is suggested to maintain levels in the optimal range and avoid over-supplementation.
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Highest, lowest vitamin D levels predict adverse pregnancy outcomes in lupus
