A study led by the University at Buffalo suggests that a gene called NANOG, named after a mythical Irish land of eternal youth, can improve nerve regeneration and innervation after traumatic injuries. Researchers used a special delivery system to activate NANOG in a mouse model with sciatic nerve damage, leading to increased muscle and nerve development and synaptic connections. Mice with NANOG expression also showed improved motor function. The study demonstrates that NANOG can reprogram muscle cells to repair damaged parts of the neuromuscular system after nerve injuries, potentially reducing long-term disability in individuals with severe nerve injuries.
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Gene named for mythical Irish land could aid muscle function after traumatic nerve injuries
