A research team from the University of California, Irvine discovered that ophthalmic acid in the brain acts as a neurotransmitter similar to dopamine in regulating motor function, offering a new therapeutic target for Parkinson’s disease and other movement disorders. Ophthalmic acid binds to calcium-sensing receptors in the brain, reversing movement impairments in Parkinson’s mouse models for over 20 hours. This discovery challenges the long-held belief that dopamine is the exclusive neurotransmitter in motor function control. The team is developing products to enhance the brain’s ability to synthesize ophthalmic acid, offering promising new avenues for movement disorder research and treatment.
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Brain molecule reverses movement deficits of Parkinson’s, offering new therapeutic target
