The review explores the therapeutic potential of liver X receptor beta (LXRβ) in treating depression and anxiety by shedding light on its role in neuroscience and psychiatry. LXRβ deficiency in female mice leads to anxiety-like behavior, while activation of LXRβ in the amygdala exerts anxiolytic effects. The review also suggests potential connections between LXRβ and autism spectrum disorder, raising questions about novel intervention strategies. Further research is needed to determine the effectiveness of LXRβ-targeted therapies in treating neurological and neuropsychiatric diseases. The findings highlight the interconnectedness of biological systems and emphasize the need for a holistic approach to mental health.
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