Smoking cessation drug development has stagnated. Here’s why

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In 2022, 5 out of 6 Americans who tried to quit smoking failed, highlighting the lack of effective treatment options for this deadly addiction that kills 480,000 people annually in the U.S. The current smoking cessation drugs on the market have limited success rates, come with side effects, and have not seen any new developments in nearly two decades. This situation, according to Nora Volkow of the National Institute on Drug Abuse, is unacceptable and contrasts with the progress seen in other medical conditions like HIV and Covid. There is a critical need for new and more effective smoking cessation drugs to help people quit successfully.

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