NIH awards multi-million grant for groundbreaking organ transplantation research

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The Terasaki Institute for Biomedical Innovation received a multi-million grant from the NIH to research organ transplantation and antibody-mediated rejection. The funding will support the development of a multi-organs-on-a-chip platform to study transplant rejection and immune tolerance. Organ transplantation is effective but requires immunosuppressive therapy that poses health risks. Current preclinical models do not accurately reflect human immune responses in transplantation, highlighting the need for advanced research tools. Dr. Vadim Jucaud will focus on creating a cutting-edge model to study rejection and tolerance mechanisms in liver and heart allografts. The goal is to improve treatment strategies and outcomes for transplant patients.

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