A systematic review found that long-term use of muscle relaxants can benefit patients with painful spasms, cramps, and neck pain, but not for low back pain, fibromyalgia, or headaches. Certain muscle relaxants like Baclofen, orphenadrine, carisoprodol, and methocarbamol were effective in reducing pain intensity and improving cramp frequency, while others like tizanidine showed benefits for neck pain and headaches. However, adverse effects like sedation and dry mouth were common. Researchers recommend careful consideration and monitoring of muscle relaxant use, especially in older patients. The study was conducted by Benjamin J. Oldfield, MD, MHS, and funded by the National Institute on Drug Abuse.
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Muscle Relaxants for Chronic Pain: Where Is the Evidence?
