New research presented at the European Society of Cardiology Congress shows that a single combined measure of three modifiable biomarkers in healthy women at midlife can predict 30-year risk for future cardiovascular events. The study, led by Paul M. Ridker and colleagues, looked at high-sensitivity C-reactive protein, LDL cholesterol, and lipoprotein(a) levels in nearly 28,000 initially healthy women. The researchers found that these biomarkers independently predicted overall risk, with the greatest impact occurring when all three biomarkers were included together. This research highlights the importance of evaluating lifelong risk beyond traditional short-term estimates in women with cardiovascular disease, which often goes underdiagnosed and undertreated.
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Measuring three factors can predict women’s 30-year risk for heart disease
