Disruption of circadian clock linked to accelerated colorectal cancer progression

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Research from the University of California, Irvine shows how disruption of the circadian clock can accelerate colorectal cancer progression by affecting the gut microbiome and intestinal barrier function. This discovery opens up new prevention and treatment strategies for the disease. Clock disturbances, particularly through lifestyle choices like extended light exposure and late-night meals, may contribute to the rise in early-onset colorectal cancer cases. The study found changes in gut bacteria diversity and abundance when the circadian clock is disrupted in the presence of cancer. Further research is needed to understand how these changes can lead to cancer development and potential prevention strategies.

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