A new study led by Johns Hopkins Medicine researchers examined the impact of obesity on muscle structure in patients with heart failure with preserved ejection fraction (HFpEF), a common form of heart failure. The study found that obesity contributes to abnormalities in muscle structure, regardless of the presence of diabetes. The study also highlighted the effectiveness of diabetes and obesity drugs in treating HFpEF symptoms. The researchers used an electron microscope to analyze muscle tissue from patients with HFpEF caused by diabetes and obesity, finding significant abnormalities in the tissue of obese patients. These findings offer insights into potential therapies for HFpEF patients.
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Study reveals obesity’s impact on muscle structure in heart failure with preserved ejection fraction
