Professor Seo Dae-ha and his team at DGIST developed Fourier transform-based plasmonic dark-field microscopy to observe the behavior of motor proteins in cells. They studied the movement and rotation of endosomes, which transport materials within cells using motor proteins along microtubules. The microscopy technique captures scattering signals of nanoparticles in real-time, revealing temporal patterns in the rotational movements of endosomes. The team compared this movement to the reinforcement learning strategy of navigation robots. This research sheds light on efficient material transport within cells and has implications for understanding and diagnosing diseases. The study was funded by various research programs and published in Advanced Science.
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Revolutionary real-time microscopy unveils secrets of motor protein behavior
