Researchers have developed a modified peptide derived from the natural CART peptide, which has shown promising results in reducing appetite, aiding weight loss, and improving metabolism in obese and prediabetic mice. The modified peptide has been found to reduce Tau protein pathology in the brain and promote the formation of new nerve cells, suggesting potential benefits for Alzheimer’s disease. The new compound, developed at the Institute of Organic Chemistry and Biochemistry, has passed tests in cell culture and animal models and has shown efficacy in targeting obesity and neurodegenerative diseases. Further research aims to understand the mechanism of action and receptor binding of the compound.
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Promising peptide compound can decrease appetite and protect the brain against Alzheimer’s-type diseases
