Middle-aged patients with severe obesity may experience improved hormonal balance proportional to weight loss after bariatric surgery or dietary intervention. In a study of 61 adults, men saw a 0.6% increase in total testosterone levels for every kilogram lost, while women experienced a 0.8% decrease. Women undergoing Roux-en-Y gastric surgery had the greatest testosterone reduction, and sleeve gastrectomy led to a significant rise in sex hormone–binding globulin levels. Ongoing hormone monitoring is vital for optimal health outcomes in bariatric patients. Limitations include sample size and lack of randomized data. This study emphasizes the importance of hormone level monitoring in obese patients undergoing weight loss treatment.
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‘Positive’ Hormone Changes Found With Weight Loss in Obesity
