Two HIV vaccine regimens in Africa failed to reduce new infections during a 3-year trial, leading to the trial being stopped based on advice from independent advisors. The vaccines did not prevent HIV infections and showed more infections in the vaccine arms compared to the placebo arms. The low incidence of HIV infections in the placebo arms raised questions, leading researchers to await further experiments for clarification. Despite the failures, researchers noted that risk reduction counseling and the use of proven HIV prevention tools have helped in lowering new infections over time. More findings from the trial are expected later this year.
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Experimental HIV vaccines fail to reduce infections in trial
