Research by Dr. Bryan McCabe and his team at Columbia University’s Brain Mind Institute has identified a protein called Trio that may reverse the decline of connections between muscles and neurons as we age. The protein plays a crucial role in maintaining the “plug and socket” connection vital for muscle function. By artificially boosting Trio levels in fruit flies, researchers were able to prevent age-related damage to these connections, leading to improved motor function in older flies. Understanding the role of Trio offers potential for developing therapies to combat age-related muscle decline in humans.
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