Sleep disturbances are common in menopausal women, with up to 69% reporting issues. Estrogen effectively treats hot flashes but not sleep disturbances. Cognitive behavioral therapy for insomnia is the gold standard treatment. Research is ongoing to better understand the neuronal circuits involved and develop more targeted therapies. Chronic sleep deprivation can impact work, relationships, mood, pain, brain fog, and overall quality of life for women. Nonhormonal medications that target neurokinin receptors show promise in improving sleep quality. Behavioral therapy remains the most effective treatment for menopausal sleep disturbances. Alcohol and exercise can also impact sleep quality during menopause.
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Brain receptors may present therapeutic target for sleep disturbances in menopause
