Researchers from The University of Queensland have discovered how Haemophilus influenzae, a common bacterium, manipulates the human immune system during respiratory infections to cause persistent illness. The bacterium can turn off the body’s immune responses, leading to chronic infections in vulnerable groups such as those with cystic fibrosis, asthma, and the elderly. The research, led by Professor Ulrike Kappler, found that the bacterium can deactivate the immune system, causing limited production of inflammation molecules. This unique ability allows the bacteria to live in respiratory tract cells and potentially worsen infections. Future research will focus on developing treatments to enhance the immune system’s ability to combat these infections.
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UQ study offers insights into how Haemophilus influenzae manipulates the immune system
