A study published in Translational Psychiatry suggests that vitamin D supplementation in individuals with a deficiency may reduce the risk of major depression. The study used Mendelian randomization analysis to determine the causal effect of vitamin D levels on chronic pain and depression outcomes. The analysis found an association between genetically predicted vitamin D levels and depression in individuals with low circulating vitamin D. However, no significant associations were found for other outcomes like fibromyalgia and chronic pain. The study indicates that vitamin D supplementation may be beneficial for individuals with a deficiency but may not provide additional benefits beyond a certain threshold level. More research is needed to fully understand the impact of vitamin D supplementation on mental health.
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Targeted vitamin D supplementation may lower depression risk for deficient individuals, study finds
