A single-center study found that shifting the timing of nutritional insulin from pre- to post-prandial reduced the risk of hypoglycemia without affecting severe hyperglycemia rates or hospital length of stay. The retrospective study at a community hospital included adult inpatients receiving nutritional insulin, with outcomes showing reduced rates of any hypoglycemia following the intervention. However, there was no significant change in rates of moderate hypoglycemia or severe hyperglycemia. The authors noted potential safety concerns with preprandial insulin dosing in unpredictable inpatient settings. While the study had limitations, it provides insight into improving insulin administration in hospitalized patients.
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Shifting Insulin Meal Timing Cuts Hospital Hypoglycemia
