Experts emphasize the need for improved care for women with epilepsy during pregnancy. It is crucial to prioritize seizure control while reducing exposure to potentially harmful medications. The latest data suggest a decline in major congenital malformations with the use of safer antiseizure medications. Valproate and topiramate are considered high-risk drugs, while lamotrigine and levetiracetam are safer options. Dose optimization and monitoring of ASM serum levels are essential during pregnancy. Folic acid supplementation is recommended for all women of childbearing age with epilepsy. Planning pregnancies and choosing the right ASM are critical for ensuring a healthy outcome for both the mother and child.
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