Research published in Circulation found that people in their 50s with severe peripheral artery disease (PAD) are more likely to undergo leg amputation within one to five years after emergency surgery to restore blood flow compared to people in their 80s. PAD is when arteries narrow due to cholesterol deposits, affecting blood flow to lower limbs. Modifiable risk factors for PAD include smoking, diabetes, hypertension, and abnormal cholesterol. The study analyzed data from over 94,000 adults over 50 with PAD who underwent surgery in England from 2013 to 2020 and found that older patients had a higher risk of death but lower risk of amputation.
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People in their 50s with PAD found to be at higher amputation risk than older people after leg surgery
