Labetalol, Nifedipine: Outcome on Pregnancy Hypertension

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Research compared the use of labetalol and nifedipine for treating chronic hypertension during pregnancy and found no significant differences in maternal or neonatal outcomes. The study included 2292 participants with mild chronic hypertension and compared the occurrence of adverse events and the effectiveness of both medications. Results showed that both labetalol and nifedipine were similarly effective in reducing the risk of adverse maternal and perinatal outcomes. Labetalol was found to have fewer adverse events and be better tolerated compared to nifedipine. The study supports the use of either medication as initial first-line agents for managing mild chronic hypertension in pregnancy.

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