Genetic Testing Could Reveal Risk of anaphylaxis

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A new study suggests that individuals with elevated levels of an enzyme called α-tryptase, encoded by the TPSAB1 gene, are more prone to severe food allergies. This finding could lead to a diagnostic test to identify high-risk individuals. Mast cells produce tryptase enzymes that can cause allergic reactions, including anaphylaxis. People with more α-tryptase copies tend to have more frequent and severe allergic reactions to food. This research could provide valuable insight into the severity of food allergies, helping individuals better understand and manage their condition. The study underscores the importance of early detection and intervention to prevent life-threatening reactions.

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