Hospital-onset bacteremia (HOB) in the neonatal intensive care unit (NICU) is linked to higher mortality rates, with birth weight and postnatal age identified as risk factors. A multicenter retrospective cohort study from 2016 to 2021 involving 451,443 infants found that HOB incidence was 1.1 per 1000 patient-days, with higher rates in infants with higher birth weights and older postnatal age. The study suggests that surveillance and prevention strategies for HOB could improve outcomes for infants in the NICU. However, the study had limitations, including not representing all NICU-hospitalized infants in the U.S. and potential confounders in matching infant and site-level characteristics.
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Bacteremia in NICU Linked to Increased Mortality Risk
