Dr. Ray O’Connor discusses the latest clinical studies on dementia, highlighting that dementia affects over 55 million people worldwide and is the seventh leading cause of death. Antipsychotics are commonly prescribed for managing behavioral and psychological symptoms of dementia, but they are associated with increased risks of adverse outcomes. However, antidepressant use does not appear to increase the risk of developing dementia. On the other hand, bariatric surgery has shown benefits in improving cognition and general health in individuals with obesity. Sildenafil, a phosphodiesterase-5 inhibitor, has potential therapeutic benefits for Alzheimer’s disease. Non-pharmacological interventions may also promote healthy aging in older adults with cognitive decline.
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