Despite improvements in vitamin D testing, some assays may still provide inaccurate results, leading to misclassification of patients. The CDC is working to address these issues through their Vitamin D Standardization-Certification Program. The program has led to improved accuracy in results, nudging manufacturers to reformulate tests. The Endocrine Society advises against routine testing for the general population due to uncertainties regarding the benefits of supplementation. The US Preventive Services Task Force also questions the widespread use of vitamin D tests. Efforts to improve test quality, such as the CDC’s program, may eventually provide the evidence needed to make a definitive judgment on the tests’ benefits and harms.
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