The aging population of patients with multiple sclerosis (MS) in the United States is increasing, leading to a shift in priorities in research and clinical care. Biologic age, rather than disease duration, is emerging as a key factor affecting disability progression in MS patients. Research is focusing on the impact of aging processes on MS outcomes, with efforts to slow biologic aging to potentially slow disease progression. Aging MS patients have unique needs, requiring a multidisciplinary approach to care. Specialized MS aging clinics are being established to address these needs, with a focus on preserving function and exploring novel therapies for progressive neurodegeneration.
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