A study published in Radiology reveals that brain structure and function on MRI can predict brain atrophy progression in early-stage Parkinson’s disease. Parkinson’s disease is a progressive disorder affecting over 8.5 million people worldwide, characterized by tremors, slow movement, and cognitive issues. Research focused on altered proteins in the brain characteristic of the disease, like alpha-synuclein. By analyzing brain connectivity in patients with mild Parkinson’s disease, researchers created an index to predict atrophy patterns over three years. The study suggests MRI may play a role in intervention trials to delay disease progression by considering individual-specific information.
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MRI connectome predicts gray matter atrophy progression in early Parkinson’s disease
